Chapter 10. Scientific Record Keeping
Francis L. Macrina
Barker K. 2005. At the Bench: A Laboratory Navigator, updated ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
Burroughs Wellcome Fund and Howard Hughes Medical Institute. 2006. Making the Right Moves: A Practical Guide to Scientific Management for Postdocs and New Faculty, 2nd ed, p 143–152. Burroughs Wellcome Fund, Research Triangle Park, NC, and Howard Hughes Medical Institute, Chevy Chase, MD. http://www.hhmi.org/sites/default/files/Educational%20Materials/Lab%20Management/Making%20the%20Right%20Moves/moves2.pdf.
Canfield MR (ed). 2011. Field Notes on Science and Nature. Harvard University Press, Cambridge, MA.
Kanare HM. 1985. Writing the Laboratory Notebook. American Chemical Society, Washington, DC.
Mellick AS, Rodgers L (ed). 2006. Lab Ref: A Handbook of Recipes, Reagents, and Other Reference Tools for Use at the Bench, vol 2. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
Menzel J, Weil P, Bittihn P, Hornung D, Mathieu N, Demiroglu SY. 2013. Requirement analysis for an electronic laboratory notebook for sustainable data management in biomedical research. Stud Health Technol Inform 192:1108.
Milsted AJ, Hale JR, Frey JG, Neylon C. 2013. LabTrove: a lightweight, web based, laboratory “blog” as a route towards a marked up record of work in a bioscience research laboratory. PLoS One 8:e67460.
doi: 10.1371/journal.pone.0067460. http://www.plosone.org/article/info%3A doi%2F10.1371%2Fjournal.pone.0067460.
Roskams J, Rodgers L (ed). 2002. Lab Ref: A Handbook of Recipes, Reagents, and Other Reference Tools for Use at the Bench, vol 1. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
Rubacha M, Rattan AK, Hosselet SC. 2011. A review of electronic laboratory notebooks available in the market today. J Lab Autom 16:90–98. http://jla.sagepub.com/content/16/1/90.long.
Voegele C, Bouchereau B, Robinot N, McKay J, Damiecki P, Alteyrac L. 2013. A universal open-source Electronic Laboratory Notebook. Bioinformatics 29:1710–1712.
Resources from federal agencies
National Cancer Institute Technology Transfer Center’s 2009 Guide for Keeping Laboratory Records brochure:
National Institutes of Health’s (NIH) 2008 Guidelines for Scientific Record Keeping in the Intramural Research Program at the NIH:
In the National Science Foundation Office of Inspector General’s Semiannual Report to Congress of March 2009, discussion of meaningful laboratory records can be found on p 51:
The NSF’s Proposal and Award Policies and Procedures Guide, released in 2013, contains information on data sharing, record retention, and other topics relevant to this chapter. It is available at
The NIH Grants Policy Statement contains information on data sharing, record retention, and other topics relevant to this chapter. It is available at
Paper laboratory data books
University bookstores and office supply companies typically sell bound data books suitable for laboratory record keeping. Such data books come in several standard formats. The paper contained in these products may not be acid free.
Some companies specialize in data book manufacturing. Products marketed by these companies contain acid-free paper and come in standard or custom-designed formats. These companies sell directly to individual customers but usually require a minimum order. Some of their data books are carried by university bookstores.
For standard-format data books of various styles:
Scientific Notebook Company
For custom-manufactured data books:
Eureka Lab Book, Inc
Laboratory Notebook Company
For materials for archiving, including acid-free glue, archival mending tape, and acid-free boxes of varying styles and sizes:
University Products, Inc
Electronic laboratory notebooks and related information
The Food and Drug Administration’s 2003 Guidance for Industry: Part 11, Electronic Records; Electronic Signatures—Scope and Application:
MEDRAD, Inc’s 2006 Electronic Lab Notebook Project—Final Report—8/04/06: